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The concentration of a chemical in a pharmaceutical solution is also called the

  1. Osmolality

  2. Osmotic pressure

  3. Tonicity

  4. pKa

The correct answer is: Tonicity

In ophthalmic practice, the concentration of a chemical in a pharmaceutical solution is often referred to as tonicity. Tonicity is a measure of the effective osmotic pressure gradient of two solutions separated by a semipermeable membrane. It is crucial in ophthalmic solutions to ensure that they are isotonic with the tissues of the eye to prevent damage or irritation. Osmolality refers to the concentration of osmotically active particles in a solution. Osmotic pressure is the pressure that must be applied to prevent the flow of solvent across a selectively permeable membrane. pKa is the negative logarithm of the acid dissociation constant of a solution. Therefore, the most relevant term for the concentration of a chemical in a pharmaceutical solution in ophthalmic practice is tonicity.